Tuberculosis (TB) is the world’s deadliest infectious disease, taking the lives of an estimated 1.4 million people each year. The U.S. Agency for International Development (USAID) leads the U.S. Government’s (USG) global TB efforts by working with agencies and partners around the world to reach every person with the disease, cure those in need of treatment, and prevent the spread of new infections and the progression to active TB disease. USAID provides bilateral assistance in 23 countries with high burdens of TB, as well as targeted technical assistance in an additional 32 countries.