Almost half of under-five mortality is attributable to undernutrition. For children who do survive, their cognitive and physical development has been comprised. The U.S. Government has long been committed to improving nutrition throughout the world to save lives and ensure the prospects of future generations. The U.S Government Global Nutrition Coordination Plan 2016– 2021 was created to accelerate progress toward global nutrition goals, such as the World Health Assembly targets, by leveraging the vast breadth and depth of nutrition activities across the government. The Coordination Plan harnesses the power of investments through better communication and collaboration across U.S. Government agencies and departments and by linking research to program implementation. Eight agencies and departments are involved in the Coordination Plan: the Millennium Challenge Corporation (MCC), Peace Corps, U.S. Agency for International Development (USAID), U.S. Department of Agriculture (USDA), U.S. Department of Health and Human Services (HHS), U.S. Department of State, U.S. Department of Treasury, and the White House Office of Science and Technology Policy. This annual summary describes progress during the fourth year of implementation, from October 2019 to September 2020, including coordination efforts amidst the COVID-19 pandemic, and plans for the coming year.