Over 45 million people are at risk of malaria in Tanzania due to the suitable climate and topography for transmission. The major malaria vectors in most areas of the Mainland are members of the Anopheles funestus group (56.3%), followed by Anopheles arabiensis (24.9%) and Anopheles gambiae (18.8%). Tanzania, with assistance from the President’s Malaria Initiative (PMI) will use Dhibiti Malaria’s approach to increase access to quality malaria prevention, diagnosis, and treatment services in high burden regions on the Mainland and regions approaching elimination in Zanzibar.