USAID's HIV Response
USAID supports country-led efforts to combat the complex challenges of HIV in over 50 countries around the world.
Read our latest story of impactPrimary Text"AIDS can be prevented. Antiretroviral drugs can extend life for many years... seldom has history offered a greater opportunity to do so much for so many.” – Former President George W. Bush, 2003 State of the Union Address, announcing the creation of the U.S. President's Emergency Plan for AIDS Relief (PEPFAR)
As a key implementer of PEPFAR, USAID’s Office of HIV/AIDS provides global leadership to the Agency’s overall response to combat the HIV epidemic. USAID supports country-led efforts to combat the complex challenges of HIV in over 50 countries around the world.
USAID’s overall goal is to support and sustain the achievement of HIV epidemic control across these countries by:
- Providing global leadership in the development of programs that maximize impact;
- Supporting country-led strategies while applying USAID’s broad health and development expertise and specialized HIV/AIDS technical competencies; and,
- Using science, technology, and innovation to support cost-effective, sustainable, and appropriately integrated HIV/AIDS interventions at scale.
USAID continues to innovate and adapt to realize efficiencies and maintain high-quality client care. We employ a "whole of Agency" approach, leveraging our considerable development assets, including our work in health, education, democracy and governance, human rights, economic growth, and humanitarian assistance.
What We Do
Through our dedicated staff around the world, host country governments, the private sector, philanthropic organizations, multilateral institutions, civil society and faith-based organizations, people living with HIV, and with the strength of our programs, we are well positioned to advance human rights, address inequality, and end HIV as a public health threat by 2030.
Where We Work
USAID delivers life-saving HIV treatment and prevention services in over 50 countries and invests in strengthening countries’ health systems to reach HIV epidemic control.
Projects and Partnerships
Maximizing Options to Advance Informed Choice for HIV Prevention (MOSAIC)
MOSAIC is a five-year (2021-2026) global project to help adolescent girls and women prevent HIV by accelerating the introduction and scale-up of new and emerging biomedical prevention products.
Adolescents and Children HIV Incidence Reduction, Empowerment and Virus Elimination (ACHIEVE)
ACHIEVE is a five-year cooperative agreement that aims to reach and sustain epidemic control in pregnant and breastfeeding women, infants, children and youth through HIV prevention and mitigation, testing, and treatment services to achieve viral suppression.
Multilateral Partnerships
The USAID Office of HIV/AIDS actively engages with the Global Fund to Fight AIDS, Tuberculosis and Malaria, UNAIDS, WHO and many other multilateral partners in the fight against HIV.
Global Health Supply Chain – Procurement and Supply Management
The project focuses on the safe, reliable supply of lifesaving medicines and diagnostics for HIV/AIDS, malaria, family planning and reproductive health, maternal, newborn and child health, and other health programs.
Stories of Impact
Diving into DREAMS: Our latest updates and stories
DREAMS (Determined, Resilient, Empowered, AIDS-free, Mentored and Safe) is a partnership developed by the U.S. President’s Emergency Plan for AIDS Response (PEPFAR). The DREAMS goal is to reduce HIV prevalence among AGYW ages 10 to 24 in 16 countries with high rates of HIV. DREAMS operates across multiple sectors including health, economic growth, education, and civil society engagement.
Celi's story: How a young woman in South Africa leads the way to prevent HIV
Celimpilo “Celi” Heather Nkambule, 27, lives in Katlehong, South Africa, where HIV prevalence is high. After discovering that a friend of hers has HIV, Celi was motivated to help other women in her community learn how to avoid contracting the virus.
“When You Share Your Story, You Give Courage to Others
Violet and Thereza are two of millions of people whose lives have been saved through PEPFAR. As of 2022, approximately 20 million people living with HIV in 54 countries received PEPFAR-supported ART.
'Every generation has to step up’: Our HIV/AIDS Staff Reflect on PEPFAR’s Impact
“The first child that died in front of me suffered from AIDS,” says Ryan Phelps, a medical officer who works in USAID’s Office of HIV/AIDS. “This made me deeply sad, and livid. We all have instances that define who we are. Moments that leave marks that are no less permanent than a tattoo…or deep scar. That was when my PEPFAR story started.”